chr15:32994756:T>C Detail (hg19)

Information

Genome

Assembly Position
hg19 chr15:32,994,756-32,994,756
hg38 chr15:32,702,555-32,702,555 View the variant detail on this assembly version.

HGVS

[No Data.]
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

JP HGVD:[No Data.]
ToMMo:0.159
NCBN:[No Data.]
NCBN(Hondo):[No Data.]
NCBN(Ryukyu):[No Data.]
East asia ExAC:[No Data.]

Prediction

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.126 colorectal cancer Near GREM1, we found using fine-mapping that the previously-identified associati... BeFree 21655089 Detail
0.003 colorectal carcinoma Near GREM1, we found using fine-mapping that the previously-identified associati... BeFree 21655089 Detail
<0.001 colorectal carcinoma In a large series of colorectal cancer cases and controls, SNPs near GREM1 and S... BeFree 18084292 Detail
0.126 colorectal cancer GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorecta... BeFree 24586997 Detail
0.125 Colorectal Neoplasms [A genome-wide association study identifies colorectal cancer susceptibility loc... GAD 18372905 Detail
<0.001 colorectal cancer In a large series of colorectal cancer cases and controls, SNPs near GREM1 and S... BeFree 18084292 Detail
0.003 colorectal carcinoma GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorecta... BeFree 24586997 Detail
<0.001 colorectal carcinoma GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorecta... BeFree 24586997 Detail
0.125 Colorectal Neoplasms [Meta-analysis of new genome-wide association studies of colorectal cancer risk.... GAD 21761138 Detail
<0.001 colorectal cancer GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorecta... BeFree 24586997 Detail
0.009 colorectal carcinoma Among the European CRC-susceptibility SNPs, rs4939827 in SMAD7 was associated wi... BeFree 23875689 Detail
0.162 colorectal cancer Among the European CRC-susceptibility SNPs, rs4939827 in SMAD7 was associated wi... BeFree 23875689 Detail
0.014 Malignant tumor of colon A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PM... BeFree 23434150 Detail
0.009 colorectal carcinoma We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.013 colorectal cancer We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.003 colon carcinoma A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PM... BeFree 23434150 Detail
0.006 Malignant tumor of colon A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PM... BeFree 23434150 Detail
0.008 colorectal carcinoma We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.010 colorectal cancer We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.004 colorectal carcinoma We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.126 colorectal cancer We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.004 Malignant tumor of colon A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PM... BeFree 23434150 Detail
0.162 colorectal cancer We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.004 colorectal cancer We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.003 colorectal carcinoma We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
<0.001 colorectal carcinoma We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.005 colon carcinoma A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PM... BeFree 23434150 Detail
0.011 colon carcinoma A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PM... BeFree 23434150 Detail
0.171 colorectal cancer We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
0.002 colorectal carcinoma We used meta-analysis of an efficient empirical-Bayes estimator to detect potent... BeFree 22367214 Detail
Annotation

Annotations

DescrptionSourceLinks
Near GREM1, we found using fine-mapping that the previously-identified association between tagSNP rs... DisGeNET Detail
Near GREM1, we found using fine-mapping that the previously-identified association between tagSNP rs... DisGeNET Detail
In a large series of colorectal cancer cases and controls, SNPs near GREM1 and SCG5 were strongly as... DisGeNET Detail
GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorectal cancer. DisGeNET Detail
[A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p... DisGeNET Detail
In a large series of colorectal cancer cases and controls, SNPs near GREM1 and SCG5 were strongly as... DisGeNET Detail
GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorectal cancer. DisGeNET Detail
GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorectal cancer. DisGeNET Detail
[Meta-analysis of new genome-wide association studies of colorectal cancer risk.] DisGeNET Detail
GREM1-SCG5 rs4779584 polymorphisms may increase the risk of developing colorectal cancer. DisGeNET Detail
Among the European CRC-susceptibility SNPs, rs4939827 in SMAD7 was associated with a significant dec... DisGeNET Detail
Among the European CRC-susceptibility SNPs, rs4939827 in SMAD7 was associated with a significant dec... DisGeNET Detail
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 familie... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 familie... DisGeNET Detail
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 familie... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 familie... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 familie... DisGeNET Detail
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 familie... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
We used meta-analysis of an efficient empirical-Bayes estimator to detect potential multiplicative i... DisGeNET Detail
Gene
-
dbSNP
rs4779584 dbSNP
Genome
hg19
Position
chr15:32,994,756-32,994,756
Variant Type
snv
Reference Allele
T
Alternative Allele
C
ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
PASS
Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
rs4779584
Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
0.1594
Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
2671
Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
16760
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